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副教授

李霞老师简介

作者: 发布时间:2025-01-07



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博士 / 副教授、硕导

EMAIL/lixia@lcu.edu.cn

科研方向/ 分析化学电化学,生物分析传感、柔性传感器构筑

讲授课程

大学化学》、《化学前沿》、《仪器分析实验物理化学实验

基础分析实验

教育及工作经历

2021.1--至今,伟德bv1946官网首页 副教授

2013.7-2020.12伟德bv1946官网首页,讲师

2021.8-2022.9 中科院上海应用物理研究所 访学学者

2015.4-2019.4 山东大学 分析化学 博后

2011.1-2012.7 香港大学 化学系 研究员助理(Pro. Yingsing Fung

2009.3-2013.7 中科院长春应用化学研究所 分析化学博士

2006.7-2009.3 长春理工大学 应用化学 硕士

2002.9-2006.6 伟德betvlctor1946 化学,学士

主持科研项目

1. 山东省自然科学面上基金,资助额度:20万,主持

2. 山东高等学校科技计划重点项目,资助额度:10万,主持;

3. 聊城市重点研发计划主持

4. 伟德betvlctor1946自然科学基金,主持

5. 山东省教指委教改项目(2022),主持;

6. 伟德betvlctor1946本科教学教改面上项目(2023);主持

7. 山东省教研院教改项目(2023)主持;

8. 丝素蛋白组合物化妆品关键技术研发,横向课题 (2024)主持

获奖

科研获奖:

山东化学化工学会科学技术奖二等奖(2023年)

山东省高等学校科学技术二等奖(2019年)

伟德betvlctor1946优秀科研成果自然科学奖等奖2022年)

教学获奖:

伟德betvlctor1946教学成果奖一等奖22021年)

山东省优秀硕士学位论文指导教师(2019年)

山东省研究生优秀成果奖三等奖(指导教师,2020

伟德betvlctor1946优秀学论文指导老师 2018

山东省大学生创新大赛产业命题赛道校级铜奖指导教师(2024

主要成果 (近几年发表科研论文)

1. Bigxin Liu, Xia Li*, Xanli Li, Fengqi Zhang, Jiajing Xie, Ensheng Xu, Qi Zhang,  shan Liu, Qingwang Xue*. An advanced 3D DNA naneplatfoma for spatiotemporally confined enhanced dual-mode bissensing, micRNA in cancer cell. Biosens. Bioelectron., 2024. 263,116619.

2. An anti-interference PEC-ECL biosensing for cancer-related gene based on self-supporting semi-encapsulated heterojunction modulated interface polarity-switching. Xia Li, Hui Yuan, Qi Zhang, Xiuhua Yuan, Chen-Zhong Li*, Qingwang Xue*. Sensors and Actuators: B. Chemical, 2025, 425, 136962

 3. Bingxin Liu, Yanli Li, Lei Du, Fengqi Zhang, Yeling Liu, Jiuming Sun, Qi Zhang, Chenzhong Li, Xia Li*, Qingwang Xue*. “One-to-many” signal-output strategy-based CRISPR/Cas12a system for sensitive label-free fluorescence detection of HBV-DNA. Spectrochim. Acta. A Mol. Biomol. Spectrosc., 2024, 304, 123338.

 4. Xia Li, Bingxin Liu, Liqi Liu, Hui Yuan, Yanli Li, Bingqian Zhou, Jiuming Sun, Chenzhong Li, Qingwang Xue. Large-scale assembly of geometrically diverse metal nanoparticles-based 3D plasmonic DNA nanostructures for SERS detection of PNK in cancer cells. Talanta, 2024, 266, 124958

 5. Xia Li, Liqi Liu, Fei Yin, Yeling Liu, Shuling Xu, Wei Jiang*, Rui Wang, Qingwang Xue*. In situ generation spatial confinement fluorescence RNA for sensitive and stable imaging of telomerase RNA in cells. Sens. Actuators B Chem., 2021, 345, 130414.

 6. Li-qi Liu, Fei Yin, Yu Lu, Xi-luan Yan, Ching-Chou Wu, Xia Li*, Chenzhong Li*. A light-up “G-quadruplex Nanostring” for label-free and selective detection of miRNA via duplex-specific nuclease mediated tandem rolling circle amplification. Nanomed. Nanotech. Biol. Med. 2021, 32, 102339.

  7. Xia Sun, Yeling Liu, Liqi Liu, Fei Yin, Ruixin Liu, Tianyu Guo, Xia Li*, and Qingwang Xue. Label-free amplified fluorescence detection of DNA biomarkers based on KFP polymerase-driven double strand displacement reactions and magnetic nanoprobes. Anal. Methods, 2020, 12, 3092. (封面)

8. Xia Li, Fei Yin, Xiaowen Xu, LiqiLiu, Qingwang Xue, LinTong, Wei Jiang*, Chen-zhong Li*. A facile DNA/RNA nanoflower for sensitive imaging of telomerase RNA in living cells based on “zipper lock-and-key” strategy. Biosens. Bioelectron., 2020, 147, 111788.

9. Fei Yin, Liqi Liu, Xia Sun, Laiyong Hou, Yu Lu, Qingwang Xue, Tong Lin, Xia Li*, and Chen-zhong Li*. A facile deoxyuridine /biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay. Analyst, 2019, 142, 3598.

10. Xia Li, Xiaowen Xu, Juan Song, Qingwang Xue, Chen-zhong Li*, Wei Jiang*. Sensitive detection of T4 polynucleotide kinase activity based on multifunctional magnetic probes and polymerization nicking reactions mediated hyperbranched rolling circle amplification. Biosens. Bioelectron., 2017, 91, 631.

11. Xia Li, Juan Song, Qingwang Xue, Haiyan Zhao, Min Liu, Baoli Chen, Yun Liu, Wei Jiang*, Chen-zhong Li*. Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a fluorescent liposome hybridization assembly via rolling circle amplification. Analyst, 2017, 142, 3598.

12. Xia Li, Juan Song, Qingwang Xue, Fuheng You, Xia Lu, Yancong Kong, Shuyi Ma, Wei Jiang*, Chen-zhong Li*. A label-free and sensitive fluorescent qualitative assay for bisphenol A based on rolling circle amplification/exonuclease III-combined cascade amplification. Nanomaterials, 2016, 6, 190.

13. Xia Li, Juan Song, Baoli Chen, Bing Wang, Rui Li, Huimin Jiang, Jifeng Liu*, Chen-zhong Li*. A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles. Sci. Bull, 2016, 61(4), 276.

相关成果 研究生培养

2019年获“山东省优秀硕士学位论文”

2018年获全国分析化学年会优秀墙报奖

2020年获“山东省研究生优秀成果三等奖”

2017年获“伟德betvlctor1946优秀硕士论文”

研究生学业奖学金一等奖8人次,二等奖学金6人次,已有四名研究生分别考取南京大学、东南大学、江苏大学、上海大学博士。

本科生培养:指导本科生署名发表SCI论文25人次,协助本科生申请国家级大学生创新创业项目3项,省级创新创业项目3项,校级创新创业项目5项。获山东省大学生科技创新大赛院级二等奖,校赛三等奖。






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